-
×
PROLOMET-H 50/12.5 Tablet
2 × ₹ 93.50 -
×
SUPERMET-H 50/12.5 Tablet
1 × ₹ 67.50 -
×
GLUCORED Tablet
1 × ₹ 26.00
Subtotal: ₹ 280.50
IMAT 400 mg Tablet
Uses of IMAT 400 mg Tablet
IMAT; to treat chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+) and certain types of gastrointestinal stromal tumors (GIST), systemic mastocytosis, and myelodysplastic syndrome.
How it Work
Imatinib Mesylate is a specific inhibitor of a number of tyrosine kinase enzymes. It occupies the TK active site, leading to a decrease in activity.In this condition the white blood cells start growing out of control so Imatinib is used to inhibit the growth of these cells. Hence cures leukaemia.
Common Side Effects
Common side effects include; Acne-like rash is reported very commonly. Other common adverse effects include: diarrhoea, nausea, vomiting, anorexia, hair loss.
Moreover,
Click Here To Search More Substitute
*Follow your doctor’s advice.
*Always take medicine after food.
*Take the medicine with water.
Fast Fact
As Imatinib Mesylate is a selective chemotherapeutic agent, its tolerability profile is better than previous cytotoxic agents. Adverse drug reactions (ADRs) are acceptable for a potentially fatal disease.
Frequently Asked Question
What type of inhibitor is imatinib?
Tyrosine kinases present attractive drug targets for specific types of cancers. Gleevec, a well-known therapeutic agent against chronic myelogenous leukemia, is an effective inhibitor of Abl tyrosine kinase. However, Gleevec fails to inhibit closely homologous tyrosine kinases, such as c-Src.
What drugs interact with Imatinib?
there may be an interaction between Imatinib and any of the following:
- clarithromycin, chloramphenicol, ketoconazole, ritonavir and nefazodone.
- itraconazole, clarithromycin, grapefruit juice.
- simvastatin, ciclosporin, pimozide, warfarin, metoprolol.
- paracetamol.
Is imatinib cytotoxic?
Imatinib is a cytotoxic drug which works by inhibiting the growth of abnormal cells in Philadelphia chromosome-positive acute lymphoblastic leukaemia. In this condition, the white blood cells start growing out of control so Imatinib is used to inhibit the growth of these cells.
Common combination chemotherapy regimens
| Cancer type | Drugs |
|---|---|
| Breast cancer | Cyclophosphamide, methotrexate, 5-fluorouracil, Doxorubicin, Gefitinib |
| Hodgkin’s disease | Docetaxel, doxorubicin, cyclophosphamide, Doxorubicin, bleomycin, vinblastine, dacarbazine |
| Non-Hodgkin’s lymphoma | Cyclophosphamide, doxorubicin, vincristine, prednisolone |
| Germ cell tumor | Bleomycin, etoposide, cisplatin, |
| Stomach cancer | Epirubicin, cisplatin, capecitabine, 5-fluorouracil |
| Bladder cancer | Methotrexate, vincristine, doxorubicin, cisplatin |
| Lung cancer | Cyclophosphamide, doxorubicin, vincristine, Gefitinib, Erlotinib |
| Colorectal cancer | 5-fluorouracil, folinic acid, oxaliplatin |
Be the first to review “IMAT 400 mg Tablet”
Related products
9
%
OFF
Save
₹ 13.50
Urinary Infection
₹ 145.00 price_including_tax
17
%
OFF
Save
₹ 10.00
Cold and Flu
₹ 50.00 price_including_tax
5
%
OFF
Save
₹ 16.00
Digestive
₹ 304.00 price_including_tax
10
%
OFF
Save
₹ 7.00
Medicines
₹ 63.00 price_including_tax
9
%
OFF
Save
₹ 6.50
Heart And Blood Pressure
₹ 67.50 price_including_tax
5
%
OFF
Save
₹ 4.00
Cough syrups
₹ 71.00 price_including_tax
7
%
OFF
Save
₹ 2.00
Diabetes
₹ 26.00 price_including_tax
9
%
OFF
Save
₹ 5.03
Metoprolol and Hydrochlorothiazide
₹ 52.10 price_including_tax
Reviews
There are no reviews yet.